Tuesday, March 4, 2014

VEDOLIZUMAB in Crohn's disease and ulcerative colitis

Vedolizumab in Crohn's disease and ulcerative colitis
VEDOLIZUMAB in Crohn's disease and ulcerative colitisEfficiency vedolizumaba (vedolizumab - alpha 4 beta 7 integrin antibody) developed by the Japanese pharmaceutical company Takeda Pharmaceuticals shows the results of Phase III clinical trials in patients with Crohn's disease and ulcerative colitis.

Remission was achieved in both diseases is almost half of the patients.


Side effects did not differ from established for the use of the drug in other diseases.


Crohn's disease and ulcerative colitis from chronic inflammatory autoimmune disease with seasonal meteozavisimosti.


Dress for the weather and strengthen immunity, for always cheaper to prevent than to cure.


Crohn's vs Ulcerative Colitis








Описание:

In the spectrum of inflammatory bowel diseases, Crohn's disease and ulcerative colitis are the two heavy weights. They share symptoms, but are very different. A key distinction: ulcerative colitis is localized.

"It always starts in the rectum and then proceeds up the colon. It can involve part of the colon or the entire colon," says Dr. Michael Weiss, a gastroenterologist on Lee Memorial System's medical staff.

In Crohn's disease, inflammation can occur anywhere along the digestive tract.

"Crohn's disease can affect the small intestine. There's more issues with potentially malabsorption of nutrients," says Dr. Weiss.

There's also something in the way they move. Ulcerative colitis progresses in a continuous pattern, while Crohn's skips around to different organs. It can also form lesions while leaving neighboring tissue untouched. It leads to what doctors call a 'cobblestone' appearance.

Both these illnesses are autoimmune diseases each characterized by chronic inflammation.

"We don't know what causes that. The theories are that it could be a virus or a bacteria, maybe food antigens," says Dr. Weiss.

The inflammation is responsible for the associated pain, cramps, diarrhea and bleeding. Other symptoms are weight loss and fatigue. Treatments for both are meant to control inflammation.

"We have these newer medications which are given either by IV infusion or injection. And these are medicines that are developed as antibodies against some of the factors that really promote that inflammation. Generally we can get somebody completely in remission and retain them in remission," says Dr. Weiss.

Doctors believe patients with either form of bowel disease can lead a normal and productive life.

View More Health Matters video segments at leememorial.org/healthmatters/

Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we've been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries.

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Stress does not stick sweetness

Stress does not stick sweets
Stress does not stick sweetnessStress does not stick sweets, will not benefit, but noticeable damage. Also remark, of course, we are talking about distress, for stress - the basis of a healthy life without it in any way.

Bad day? Eat cookies. Life went awry? Chocolate should help.


Sad at home? Sit in front of a TV with a glass of wine and a bowl of ice cream.


It looks like you? You are not the only person who tries to seize stress sweets. According to the researchers, in the past 50 years, consumption of processed sugar has doubled.


However, the new data show the opposite specialists process - the more sugar we consume, the greater are fueling depression.


According to the group of doctors, scientists, nutritionists, psychiatrists and psychologists who have studied the relationship between food and mental health - there is a correlation between behavioral changes and the level of sugar in the blood.


Refined sugar and products containing sugar into the body very quickly, which increases the amount of insulin produced. In connection with this oil is accumulated and not burnt, and as a result of changes in blood sugar levels. The higher the level, the instability of the our mood, and the more painful reaction to stress again that we have seized sweets - says nutritionist James Durand-List.


According to studies, the average Briton consumes 238 teaspoons of sugar a week. As the brain scans, the sugar can be addictive body like a drug.


Nutritionists recommend consuming at times of stress berries, green vegetables, turkey and nuts. Berries are full of vitamin C and also full of fiber, which helps control blood sugar levels. Vegetables replenish the body with vitamins and minerals.


Turkey contains an amino acid that produces a useful hormone serotonin. Nuts improve the immune system and are full of vitamins to help reduce, so write, stress.


Reduce, stress, stress is not necessary. Should intervene only in distress, and not always reduce, because if the lack of response to the stimulus and distress hyporesponsiveness, so it's time to whip up. The same stress.


In any case, however, does not stick stress sweets, otherwise painful meteosensitivity not be avoided.


 in the wake of MIGnews.com

Madonna - Sticky & Sweet Tour DVD Buenos Aires, Argentina - Full Show HD








Описание:

Madonna - Sticky & Sweet Tour (2008) FULL CONCERT HD
GYPSY part of the show, feat. "Kolpakov Trio" -
Vadim Kolpakov Dance: 0:56:40 Spanish Lesson, 1:05:22 La Isla Bonita,1:10:56 Doli Doli, 1:14:00 You Must Love Me,
1:17:36 Don't Cry For Me Argentina.

0:03:31 Candy Shop
0:07:15 Beat Goes On
0:11:40 Human Nature
0:15:34 Vogue
0:20:04 Die Another Day
0:23:04 Into The Groove
0:28:48 Heartbeat
0:33:39 Borderline
0:37:25 She's Not Me
0:42:05 Music
0:47:10 Rain/Here Comes The Rain Again
0:51:08 Devil Wouldn't Recognize You
0:56:40 Spanish Lesson
1:00:32 Miles Away
1:05:22 La Isla Bonita
1:10:56 Doli Doli
1:14:00 You Must Love Me
1:17:36 Don't Cry For Me Argentina
1:20:24 Get Stupid
1:23:27 4 Minutes
1:28:07 Like A Prayer
1:33:41 Ray Of Light
1:42:33 Like A Virgin
1:45:27 Hung Up
1:51:32 Give It 2 Me
1:59:25 Credits.

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THE FAR EAST catastrophic floods REVS

In the Far East, catastrophic flooding is gaining momentum in the Far East, catastrophic flooding is gaining momentum.

THE FAR EAST catastrophic floods REVS


The water level in the Amur River near Khabarovsk exceeded 730 cm and continues to rise.


In the Khabarovsk already flooded 556 houses.


By renewed rains new forecast level of water in the Amur River near Khabarovsk - 780 cm 


The current flooding is most severe in 120 years. 


Wrecking Water: Russia's Far East hit by biggest floods in 120 years








Описание:

There's no relief in sight for the tens of thousands of people living in Russia's Far East battered by the worst flooding in more than a century. Water levels have already broken a historical record for the region and are expected to reach the peak only by the middle of the week. Around 30 thousand people have already been evacuated by emergency services and authorities say this could be just the beginning. RT's Paul Scott is in the thick of events and talked to some of the victims.

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