Different strains of the most common intestinal bacteria have different effects on our health Various strains of the most common intestinal bacteria have different effects on our health, depending on whether they are allocated to the feed intestinal mucus.
Not only affects the intestinal microflora of us but we influence the microflora, and it happens due to the mucin proteins that are part of the mucus covering the intestinal epithelium. Mucins are usually associated with molecules of carbohydrates, and together they represent a rather complex structure. Different bacteria have different attitudes to the mucin: some interact with them and eat them, while others can not even stay on the wall of the intestine, if there are any of mucins.
One of the most common bacteria in our microflora - Ruminococcus gnavus, which can be found in 90% of people, including infants. Of R. gnavus health depends on the gastrointestinal tract, if the proportion of the bacteria to deviate from the norm, this may lead to inflammatory bowel disease. It is also known that this bacterium has never averse to eat mucins.
Bacteria R. gnavus (photo Kathryn Cross / Institute of Food Research).
However, researchers from the Institute of Food Research in Norwich (UK) noted that different strains have different attitudes to the mucin, if one of the strains of R. gnavus can easily be fed solely by mucins, the other on such a diet for a long time did not comply. As expected, were between genetic variation.
Thus, the body can choose for myself with what bacteria to live, providing some food and starving others. (It is not necessary, of course, forget that bacteria may mutate so that adapt to any food conditions). However, if one of the bacterial strains better suited for utilization of carbohydrates in the mucosal layer, it means that it can be populated into the intestine neonates mucins which may be the only source of food for the bacteria. Well, then this strain can be the most intimate - literally - to the epithelial cells, simply because it can penetrate the mucus layer of mucin.
This means that when you want to find out what the cause of gastrointestinal illness in a patient, you have to take into account that different strains of the same bacteria have a significant different eating habits, but because of their interaction with the intestine and role in the development of a disease can vary greatly.
in the wake of PLoS ONE, Institute of Food Research, compulenta.computerra.ru
rheumatoid arthritis diet cure - rheumatoid arthritis home treatment
rheumatoid arthritis diet cure - rheumatoid arthritis home treatment
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To cure Rheumatoid Arthritis it is very important to do everything perfectly 'right'. However, many RA sufferers are inadvertently making their RA worse because of a lack of information or by not fully understanding the underlying cause of this disease. So today, to help you on your path to wellness, I would like to warn you about two types of drugs that can make your Rheumatoid Arthritis worse in the long run and give you some simple tools so that you can protect yourself from this problem.
The two drugs that I will discuss below can both have the effect of upsetting your digestive system in the worst possible way. These drugs create turmoil on the healthy bacteria in your intestines (which are called 'probiotics' by the supplement companies) and damage your intestinal wall leading to poor absorption of nutrients and a concept known as 'leaky gut' by Naturopaths. 'Leaky Gut' is actually a descriptive term for having holes in your intestinal wall, which then allows large foreign molecules to enter your blood. These foreign proteins entering your blood can trigger a state of 'molecular mimicry' and result in your body attacking it's own joints in a state of innocent confusion. Quite literally, by having a depleted intestinal environment you will experience worsened symptoms of RA.
So, we need to look at the following two drugs very seriously! Let us first look at Non Steroidal Anti-Inflammatory Drugs (NSAID's)
NSAID's
There are a large range NSAID's that are commonly used to treat arthritis. Research has shown that most of these drugs actually contribute to 'leaky gut' and thus perpetuate Rheumatoid Arthritis through the mechanisms I have described above. The offenders include all the common brands like Advil, Motrin, Naprosyn and so on, with the only exceptions being aspirin and nabumetone (Relafen). [1] It has been shown that these drugs can increase intestinal permeability (holes in the intestinal wall) within 24 hours [2]
My personal experience matches these findings. The first medication I took for my RA was one of the leading NSAID brands. It was fantastic at relieving my pain for about 2 weeks. As time wore on the effects of the drug diminished and so after about 3 weeks I decided to see how I felt once I stopped taking the drug. After stopping this medication I felt about twice as bad as what I was before I started taking it. Looking back I believe that my intestinal wall took a battering during this time, which in turn led to increased swelling and pain.
I learnt most about my body and my food intolerances by remaining off these drugs. These drugs interfere with the critically important communication that occurs, via pain levels, from eating a food and monitoring its effect on your body. By cutting out the pain with a drug I was losing all the information I needed to create a diet free of offending foods.
Since NSAID's are common and are available over the counter we think that they can't be too harmful for us. It couldn't be further from the truth. If you are stuck at the moment on these drugs due to persistent pain levels then that's OK - pain relief and protection from joint damage in the short term is obviously of paramount importance - but I'll show you below some great ways to offset the long term effects whilst you wean yourself off these drugs.
But first, lets look at another drug that is wreaking havoc on your insides:
ANTIBIOTICS
To start our discussion of antibiotics and their effect on the body, we first need to talk about something a little unusual - your intestinal bacteria...
In an ideal state of health you would have between 2-4 pounds of bacteria living inside your intestines in numbers upwards of 40 Trillion. This may sound like the premise of a horror film, but don't freak out, the vast majority of organisms living in there are helpful, or at least not harmful, to our lives. Beneficial Bacteria (also called Probiotics or Microflora) are the good bacteria that live inside us with the majority found between the end of the small intestine and the distal colon. These tiny organisms are absolutely imperative to our health and we should really think of this big mass of mini life as a vital organ like a lung or a kidney.
The many important functions that our bacteria perform for us includes killing harmful bacteria, killing fungus (also known as candida), and building B vitamins for the rest of our body to use. They also help our bodies produce enzymes, help to change the acidity within our cells and play an important role in the development of the immune system by maintaining a constant dialog with our internal bodies through the surface of the gut. Our microflora also influences many of our hormones. So this healthy bacteria is very important stuff.
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