Meet the Orionids meteor shower Meet the Orionids meteorshower from Halley's Comet.
Orionids, as the name implies, visually enter the Earth's atmosphere from the constellation Orion.
Hinder watch this beautiful phenomenon may, unless clouds and the moon, which began to decline only after the full moon October 19, 2013.
Astronomers are advised to observe the fall of the celestial bodies in the open at night. Orionids, like all the streams of meteors, named after the constellation from which, as it appears visually, they take off - in this case, the constellation of Orion.
Recall that this meteor shower can be seen to develop in two year: in the spring, in May as Aquarids (the radiant in the constellation of Aquarius), with a maximum of 5 May and autumn - Orionids with a maximum on October 21-22.
New anticoagulantsrequire new antidotes New anticoagulants that are embedded into the clinic for the treatment of patients with atrial fibrillation, reconstructive operations on the locomotor system and others like them require new antidotes, and they will soon, it is thought, will appear.
Was another phase of the study possible antidote to new oral factor Xa inhibitors with a primary PRT4445 andeksanet called alpha, apixaban inhibitory effect by 90% within two minutes after intravenous bolus maintaining at this level during the two hour infusion.
Without the development of these antidotes, there is a real danger of uncontrolled bleeding.
Andeksanet alpha is similar to factor Xa, competitively blocking the inhibitory effects of apixaban, rivaroksaban'a, enoxaparin, and developed edoksabana betriksabana.
The main study of a new drug for FDA approval is planned for 2014.
In the meantime, essence of the case, the question is - or well-tested warfarin or new anticoagulants, without waiting for the antidote.
Atrial fibrillation and others like her, the pathological processes of cohort meteodependent states.
Major Side Effects Associated With Use of Pradaxa - NY Attorney Dan Burke of Parker Waichman
Attorney Dan Burke of Parker Waichman explains the side effects of using the prescription drug Pradaxa.
Pradaxa is an anticoagulant which basically means it prevents blood from clotting. Although there are other drugs that are used to treat the same condition, the manufacturers of Pradaxa promoted the drug stating that it didn't have the same issues as those other drugs. However, it has a very strong flaw that is causing massive health complications. With each of the drugs, you have the possibility to have a bleeding event. What this means is that when you bleed, it won't stop. Plus, with Pradaxa bleeding events can be caused by minor events that wouldn't make a normal person begin to bleed out. The flaw with Pradaxa is there is no current way to stop the bleeding quickly. You may even need dialysis to help you recover and that's if you have enough time. Watch this video now to learn more.
To learn more about prescription drug law, I encourage you to watch the video above and to explore our educational website at http://www.yourlawyer.com/topics/over.... If you have legal questions, I want you to call me at (800) 800-9797. I welcome your call. Dan Burke Parker | Waichman LLP 6 Harbor Park Drive Port Washington, NY 11050 (800) 800-9797 http://yourlawyer.com
Every tissue of the human body has its own built-in biological clock gene Scientists from the University of California (Los Angeles), led by professor of genetics and biostatistics Steven Horvath found that every tissue of the human body has its own built into the genome of the biological clock, just showing its age.
Aging fabrics in accordance with this clock is uneven, for example, breast tissue aging faster and slower heart.
To understand the rate at which time flows through various parts of the body, Horvath and his colleagues as a universal measuring instrument chosen DNA methylation - a natural process of chemical modification of DNA, which is one of the most important epigenetic mechanisms involved in the regulation of gene expression. Studied nearly 8000 different 51 types of samples of both healthy and cancerous cells and tissues, the authors monitored as age affects the levels of DNA methylation in them from prenatal period up to 101 years. As a result, it has been allocated 353 present in the body throughout the DNA marker methylation levels which vary significantly in the aging process and can be used as the biological clock.
The effectiveness of such a time meter was tested by comparing the biological and chronological age in various organs and tissues. Although in most cases these figures match, to the surprise of the authors, this was not always the case. Thus, a healthy heart muscle tissue were approximately nine years under their chronological age and female healthy tissue breast, conversely, age faster rest of the body, leaving behind it on average two to three years.
In this case, that was another surprise for the authors, the cells of children with progeria - a genetic disease that causes premature aging - were quite relevant to their chronological age.
At the same time, in the case of cancer, tissue adjacent to the tumor is on average over 12 years, and tumor cells - 36 years older than other tissues. Biological age some tissues taken from tumors of the brain in infants, ahead of the rest of the body at 80.
As suggested by Horvath, these data explain why breast cancer - the most common type of cancer in women, and why age is a risk factor for cancer in both sexes.
Another discovery was the discovery of uneven progress of the biological clock - after birth, throughout childhood and adolescence, they are ticking quickly, then slow down to 20 years and are starting to go more smoothly.
Applying their method to pluripotent stem cells - mature body cells, reprogrammed into embryonic able to specialize in almost all cell types, Horvath and his colleagues found that their biological age corresponds to the newborn.
The process of transforming adult cells into pluripotent actually nullifies their biological age. This shows that the process of restarting the biological clock in principle possible. Another question is how the biological clock controls the aging process.
If you find that this is the case, then therapeutic intervention in this mechanism can be a tool to achieve eternal youth.
The future plans of the scientists to see how stop biological clock will affect the aging process and it will not lead to an increased risk of cancer. In addition, the researchers plan to determine whether there is a similar mechanism in mice.
in the wake of Medportal.ru
Humans Can Be Dated Like Trees
Описание:
Like rings on a tree, human flesh can be dated in a consistent, reliable way. And as Trace tells us, this discovery could revolutionize medicine, and even enable us to extend life.
Read More:
UCLA scientist uncovers biological clock able to measure age of most human tissues http://www.uclahealth.org/body.cfm?id... "Everyone grows older, but scientists don't really understand why. Now a UCLA study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process."
UCLA scientist uncovers biological clock able to measure age of most human tissues http://www.eurekalert.org/pub_release... "Everyone grows older, but scientists don't really understand why. Now a UCLA study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process."
DNA methylation age of human tissues and cell types http://genomebiology.com/2013/14/10/R115 "It is not yet known whether DNA methylation levels can be used to accurately predict age across a broad spectrum of human tissues and cell types, nor whether the resulting age prediction is a biologically meaningful measure."
Women's breasts age faster than the rest of their body http://www.newscientist.com/article/d... "Breasts typically age more quickly than the rest of the female body. So suggests a system that may be the most accurate way yet of identifying a person's age from a blood or tissue sample."
Why We Age -- Theories and Effects of Aging http://longevity.about.com/od/longevi... "The study of aging - gerontology - is a relatively new science that has made incredible progress over the last 30 years."
ARE TELOMERES THE KEY TO AGING AND CANCER? http://learn.genetics.utah.edu/conten... "Inside the center or nucleus of a cell, our genes are located on twisted, double-stranded molecules of DNA called chromosomes."
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New anticoagulants that are embedded into the clinic for the treatment of patients with atrial fibrillation, reconstructive operations on the locomotor system and others like them require new antidotes, and they will soon, it is thought, will appear.
Scientists from the University of California (Los Angeles), led by professor of genetics and biostatistics Steven Horvath found that every tissue of the human body has its own built into the genome of the biological clock, just showing its age.