Than just a burden to old age is not the case, so that at telomeres world is large enough Old age is a burden not only to telomeres, but also to aging, when the spirit of age.
Active life - the most important tool longevity and telomeres is not a hindrance.
But, as Holbach, death is also a natural state, and it is necessary and important that everything had its place.
In any case, the biological clock, created by Nature, has not been canceled.
Administration http:///
Old age - a burden telomeres
According to the philosophical outlook, everything in the universe is in a cyclical change. Therefore, any life that passes through the birth process, and the existence of aging invariably enters the gates of death. However, this in no way weakens the efforts of scientists that are configured to unravel the secrets of aging and a tablet from senile debility.
Since ancient times, people have been trying to find a cure for old age, and a pill of immortality. It has intrigued mankind since the time of the pharaohs, continued to harass the alchemists of medieval Europe and remains relevant today. This is understandable, who does not want to live forever and stay young?
And this requires something just a little - to stop the aging of cells.
After all, there are also timeless in nature organisms. For example, cells can divide begonias almost endless. Ascidians (Ascidiae), invertebrate animals, which are also almost never get old. There are so-called hydra Fusco.
As long as the temperature remains above 20 ° C, it is divided, produce offspring and does not age. True if the temperature goes down, it dies. Why do some organisms can live a very long time, while others are not capable of?
Life expectancy depends on the ability of the body's cells to make up the loss so as to prevent any violations of the fabric. Currently, there are many different theories of aging. Among them are genetic theories: the theory of programmed death and mutation accumulation theory. There is also a group of theories called probabilistic. According to them, the aging process is the result of random processes at the molecular level.
This group includes the theory of free radicals, apoptosis (cell suicide) and others.
Cell sverhpredel
To date, the greatest impact in the society received a genetic theory of telomeres. In 1961, American gerontologist L. Hayflick by simple experiments found that skin fibroblasts can be shared outside the body about 50 times. Hayflick tried to freeze fibroblasts after 20 divisions, and then a year later defrosted. And they shared an average of 30 more times, that is up to the limit. This is the maximum number of divisions for a particular cell was called the Hayflick limit.
But what caused such limits are only a guess after 10 years.
One day, our compatriot, the Institute of Biochemical Physics, Russian Academy of Sciences Alexei Matveevich Olovnikov, expecting the train in the subway. Overwhelmed with thoughts about the experiences Hayflick he looked thoughtful and suddenly it dawned on me. Like a train running on rails, the enzyme DNA polymerase moves along the DNA molecule and removes her copy. But if the train will not move from the endpoint, but somewhere in the middle of the branch, the copy will be half as long, that is not the entire genetic code will be recreated.
If this happens continuously, the genetic material becomes smaller. Over time, the end portions of the chromosomes - the telomeres (telos - end measures - part) are shorter for that reason. Olovnikov barely missed the train, but it was worth it ...
Of course, different cells have their Hayflick limit and a finite number of divisions. Certain cells of the body, such as stem cells, germ cells and cancer cells can divide indefinitely. It turned out, this is due to the presence of a special enzyme called telomerase.
It was opened in 1980 by American scientists Greider and Blackburn. Telomerase rebuilding back end portions of chromosomes - telomeres and thus prolongs the life. Incidentally, in contrast to sexual stem cells and cancer cells in conventional telomerase disabled so they can not divide indefinitely and tissues age.
Interesting, but some bacteria and viruses have circular DNA molecule that does not have telomeres (end sections) and there is nothing to be lost when copying. In this regard, the bacteria do not grow and do not require the services of telomerase.
Telomere theory of aging seemed quite slender, and studies conducted by researchers from Harvard Medical School in Boston convinced almost everyone. Ronald Depino and his colleagues experimented on mice that did not work nearly telomerase. As a result, a young age, have already emerged signs of aging.
Over time, the end portions of chromosomes - telomeres become shorter. Photo: Science Picture Co / Getty Images News
Scientists were able to recover telomerase activity and reverse the aging process. As the researchers themselves say, this was due to the activation of dormant telomerase in stem cells of animals. Keeping in mind that the high activity of the enzyme is characteristic of cancer cells, scientists have acted cautiously and avoid malignant transformation.
So, all we are waiting for immortality in the near future? Sounds good, but apparently not.
At telomeres helps those who help themselves
Olovnikov himself, the author of telomere theory, still considers it a theory. It turns out the person telomere length is shorter than that of mice, but he lives ten times longer. And in some species of mice that differ significantly in length of telomeres, the length of life remains the same.
These contradictions can not convince Olovnikova, and he is looking for the deeper mechanisms of aging.
While scientists delve into the cells, we have to wait patiently. Although not quite so ... One of the iron ways to extend the life and works everywhere confirmed in laboratories.
It is proved that if the animal undernourish, they live longer.
Scientifically it is called calorie-restricted diet, and the common people - the diet. If you eat 30% less than you would like, you will achieve the effect. Scientists attribute this to the decrease in the activity of free radicals and changes in hormonal levels.
Eat sensibly, and maybe you will be able to live up to create a pill of immortality.
http://www.epochtimes.ru
General Health
http://lifespa.com/Doctor
http://lifespa.com/cleansing
http://lifespa.com/Newsletter
We all want to make the best use of our healthcare dollars, but choosing a doctor can be a very stressful experience. Do you go to a medical doctor, an acupuncturist, a chiropractor, or a naturopath? We have many choices in the US, allowing us to choose the right doctor for the right condition.
But how do we navigate these choices?
Before we can choose a doctor, we must first choose the correct system of medicine for our needs.
There are three major healthcare delivery systems to choose from: Allopathic or Western medicine, Naturopathic medicine, and Traditional or Indigenous systems of medicine.
In fact, each of these systems of medicine plays a fundamental role in what I might call, "a balanced approach to health care." Knowing which to choose, and when, will help you create the healthcare dream team you deserve.
Join me as I explore and evaluate each of these health care systems, and build your team now, before you have an issue or illness.
________________________________________
Allopathic (Western) Medicine
Allopathic, or western, medicine is practiced by medical doctors (MDs) and is designed to save lives and eradicate the symptoms of disease. It focuses on the treatment of disease and uses pharmaceutical drugs to suppress the expression of that disease.
In general, western drugs are designed to do the job for the body. For example, if you have high blood pressure, a medicine to lower the pressure might be prescribed, with the knowledge that this drug will never treat the cause of the hypertension.
At the same time, high blood pressure for any length of time will significantly increase the risk of a heart attack or stroke. So, while the medicine will not cure the blood pressure, it may extend a life by preventing a cardiovascular event. Without this kind of intervention, many people would die unnecessarily.
The downside to western medicine is that pharmaceutical drugs often have side effects, or they stop working because the body builds a tolerance to that drug.
In the best case scenario, the drug masks pain, saves or prolongs a life. In the worst case scenario, the medications cause side effects that require more medications with more side effects. All too often, this results in a situation where medical doctors keep adding medications to address the side effects, instead of replacing the ones that are not working.
Seniors can end up stacking or combining ten or more meds, and even the best biochemist would be challenged to predict the interactions and potential side effects.
This scenario has given western medicine a bad reputation in some circles, with segments of the population totally against any sort of western medical intervention.
Personally, I feel this is a dangerous attitude.
I have seen in my practice on numerous occasions, parents reluctant to take their children to a medical doctor for a cold because of fear they would just prescribe antibiotics.
Make no mistake about it, antibiotics save lives. I have seen children die because parents waited too long to have their child seen by a doctor out of a reluctance to give antibiotics.
Are there safe and effective strategies to avoid needing antibiotics? Yes! I wrote my book, Perfect Health For Kids, to help educate parents in preventative strategies so that children's colds last just two days, rather than two weeks, while encouraging parents to use western medicine when needed.
Though, while raising our six children we have only needed antibiotics a couple of times, I would shudder to think of having to raise children without access to them or western medicine in general.
When to See Your MD:
I always tell my patients that if you are debating whether or not to go see your MD about a certain condition or symptom, you should definitely go. If you are concerned that they will only prescribe antibiotics and you want a more cause-directed approach, be careful. Do not overlook a potentially serious infection that needs urgent antibiotic treatment.
Remember, at the same time you can also consult with your traditional or naturopathic doctor about cause-based strategies, how to mitigate the side-effects of medication, and support the immune system during a course of treatment.
http://www.lifespa.com
